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Getting to Merida

From the U.S., there are direct flights into Mérida's international airport.

The most frequent come from Houston (Continental). (Delta flies to & from Atlanta, but flights out of Atlanta leave at 8 am!).  Mexicana flies from Miami via Cancun.

If the days of those flights don't fit your schedule (or you are using miles and can't get a flight to Merida) flights to Cancun are cheap and plentiful (e.g., American via Dallas-Ft. Worth).  From Cancun it's a 4-hour ride.  You can rent a car, but the drive is flat and boring, and the tolls are very expensive, not to mention gas. 

If there are only 1 or 2 of you and you don't have tons of luggage, you can take the bus from the downtown Cancun bus station (a 25-minute shuttle bus or taxi from the airport).  The Mexican buses are superb - air conditioned, rest room, comfortable seats - plus two movies en route - all for about US$25-35!